The bubonic plague, which swept across Europe between 1347 and 1353, is estimated to have killed up to one half of the continent’s population. The sudden loss of life led to the abandonment of farms, villages and fields, creating what researchers describe as a massive historical ‘rewilding’ event.

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Dravet syndrome is a genetic disorder which causes treatment resistant epilepsy and is often accompanied by speech and developmental delays. About 3,000 people are thought to have the condition in the UK. Current treatments aim to control the number and severity of seizures, but often do not work.

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"That's where he came up with the idea of starting a soda-bottling business," says Ben Hartwig.